High likelihood of actionable pathogenic variant detection in breast cancer genes in women with very early onset breast cancer.

Background: While the likelihood of identifying constitutional breast cancer-associated , and pathogenic variants (PVs) increases with earlier diagnosis age, little is known about the correlation with age at diagnosis in other predisposition genes. Here, we assessed the contribution of known breast cancer-associated genes to very early onset disease.

Methods: Sequencing of , and c.

Livestock-Associated Methicillin-Resistant From Animals and Animal Products in the UK.

Livestock-associated methicillin-resistant (LA-MRSA) is an emerging problem in many parts of the world. Although animal-adapted LA-MRSA has been known for many years, recent reports suggest a possible increasing trend in the zoonotic transmission of LA-MRSA in Europe. Since its emergence in the early 2000's, several investigations have indicated that persons in prolonged, repeated contact with affected livestock are at a higher risk of becoming colonized with LA-MRSA.

Patient experience and physician productivity: debunking the mythical divide at HealthPartners clinics.

Introduction: Physicians are continually encouraged to be more productive while providing higher levels of patient satisfaction. It is a common presumption that the two goals are somewhat exclusive-that higher productivity must entail a sacrifice in patient satisfaction or vice versa. Moreover, physicians seeking tested, evidence-based approaches to improving satisfaction have had relatively little to go on, and they commonly have justifiable concerns about how ineffective changes may hurt their productivity for no benefit.