Publications by authors named "Sarah Illersperger"

Background: It is known that kidney transplantation (KTx) decreases mortality rate and increases life expectancy about 10 years compared with dialysis, particularly in patients with diabetes. However, cardiovascular disease is still the most common cause of death after transplantation.

Purpose: The evaluation of the cardiovascular risk after successful KTx in diabetic and nondiabetic patients.

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Article Synopsis
  • The study examines arterial stiffness and phase angle (PhA) as important factors in cardiovascular health, focusing on renal transplant recipients (RTRs) using different immunosuppressant treatments, specifically belatacept (BELA) versus calcineurin inhibitors (CNI).
  • A total of 325 RTRs were analyzed, showing no significant differences in arterial stiffness or PhA among those receiving BELA, cyclosporine A (CsA), or tacrolimus (Tac), although age was identified as a key factor influencing arterial stiffness.
  • The findings suggest that while arterial stiffness and PhA are critical indicators in RTRs, further studies are necessary to understand these cardiovascular risks and the effects
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Introduction: In renal transplant recipients (RTRs), cardiovascular (CV) complications are associated with non-traditional risk factors, such as a decline in graft function, immunosuppressive therapy, time of dialysis before transplantation, inflammation and anemia. Higher value of arterial stiffness is the consequence of risk factors and it can lead to CV events. The aim of this study was the assessment of the arterial stiffness in RTRs with different value of estimated glomerular filtration rate (eGFR) and its correlation with classical and non-classical CV risk factors.

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Introduction: Arterial stiffness parameters can be used as a predictor of cardiovascular events in the general population and renal transplant recipients (RTRs). Additionally, the renin-angiotensin-aldosterone-system (RAAS) blockade mitigates arterial stiffness in the general population. There are no sufficient data concerning the role of the RAAS blockade in reducing arterial stiffness among patients after kidney transplantation.

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Objective: Arterial stiffness and altered body composition (increased body fat mass [BFM] and decreased lean body mass) are acknowledged risk factors for adverse outcomes after kidney transplantation related to cardiovascular diseases. The aim of the study was the assessment of the relationship between arterial stiffness and fat tissue parameters in renal transplants recipients (RTrs).

Methods: A group of 344 RTrs with stable disease and a mean age of 52.

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Background: Hyperlipidemia is one of the major risk factors for developing a cardiovascular disease (CVD) and it is a frequent post-transplant complication, occurring in up to 60% of the renal transplant recipients (RTRs). Lipid lowering therapy with HMG-CoA reductase inhibitors (statins) is generally recommended and may reduce the overall cardiovascular risk. The aim of this study was to evaluate the lipid profile, statin administration and their relationship with arterial stiffness parameters in RTRs.

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