Field-based body temperatures reveal behavioral thermoregulation strategies of the Atlantic marsh fiddler crab Minuca pugnax.

Behavioral thermoregulation is an important defense against the negative impacts of climate change for ectotherms. In this study we examined the use of burrows by a common intertidal crab, Minuca pugnax, to control body temperature. To understand how body temperatures respond to changes in the surface temperature and explore how efficiently crabs exploit the cooling potential of burrows to thermoregulate, we measured body, surface, and burrow temperatures during low tide on Sapelo Island, GA in March, May, August, and September of 2019.

Evaluating the performance of a decentralized graywater treatment system in a living building at Hampshire College, Amherst, MA, USA.

Decentralized graywater treatment systems are growing in popularity as the threat of water scarcity rises and wastewater's potential as a resource is recognized. In 2016, Hampshire College in Amherst, Massachusetts, completed construction of the R.W.

A Molecular Circuit Regenerator to Implement Iterative Strand Displacement Operations.

The predictable chemistry of Watson-Crick base-pairing imparts a unique structural programmability to DNA, enabling the facile design of molecular reactions that perform computations. However, many of the current architectures limit devices to a single operational cycle. Herein, we introduce the design of the "regenerator", a device based on coupled enthalpic and entropic reactions that permits the regeneration of molecular circuit components.

Mathematical models of the interrelated dynamics of hepatitis D and B.

The hepatitis delta virus (HDV) is a rarest form of viral hepatitis, but has the worst outcomes for patients.It is a subviral satellite dependent on coinfection with hepatitis B (HBV) to replicate within the host liver.To date, there has been little to no modeling effort for HDV.

Mathematical models of e-antigen mediated immune tolerance and activation following prenatal HBV infection.

We develop mathematical models for the role of hepatitis B e-antigen in creating immunological tolerance during hepatitis B virus infection and propose mechanisms for hepatitis B e-antigen clearance, subsequent emergence of a potent cellular immune response, and the effect of these on liver damage. We investigate the dynamics of virus-immune cells interactions, and derive parameter regimes that allow for viral persistence. We modify the model to account for mechanisms responsible for hepatitis B e-antigen loss, such as seroconversion and virus mutations that lead to emergence of cellular immune response to the mutant virus.

Investigation of electrophoretic exclusion method for the concentration and differentiation of proteins.

This work presents a technique termed as "electrophoretic exclusion" that is capable of differentiation and concentration of proteins in bulk solution. In this method, a hydrodynamic flow is countered by the electrophoretic velocity to prevent a species from entering into a channel. The separation can be controlled by changing the flow rate or applied electric potential in order to exclude a certain species selectively while allowing others to pass through the capillary.

Rich dynamics of a hepatitis B viral infection model with logistic hepatocyte growth.

Chronic hepatitis B virus (HBV) infection is a major cause of human suffering, and a number of mathematical models have examined within-host dynamics of the disease. Most previous HBV infection models have assumed that: (a) hepatocytes regenerate at a constant rate from a source outside the liver; and/or (b) the infection takes place via a mass action process. Assumption (a) contradicts experimental data showing that healthy hepatocytes proliferate at a rate that depends on current liver size relative to some equilibrium mass, while assumption (b) produces a problematic basic reproduction number.

The dynamics of a delay model of hepatitis B virus infection with logistic hepatocyte growth.

Chronic HBV affects 350 million people and can lead to death through cirrhosis-induced liver failure or hepatocellular carcinoma. We analyze the dynamics of a model considering logistic hepatocyte growth and a standard incidence function governing viral infection. This model also considers an explicit time delay in virus production.

Developing a model for complementary therapy for patients with cancer.

This article outlines an initiative to offer complementary therapy to patients with cancer, describing how the service was set up and funded, and the model of care. it also highlights some findings from research evidence.