Directional web strikes are performed by ray spiders in response to airborne prey vibrations.

Most orb-weaving spiders use static webs that deform only after flying prey hit the webs. However, ray spiders (Theridiosoma gemmosum) pull orb webs into cones that are loaded with enough elastic energy to snap back like slingshots at accelerations of up to 504 m s-2 once released. We test the hypothesis that ray spiders sense vibrations from flying insects to release their webs and capture prey in mid-flight.

The Impact of a Nursing-Led Intervention Bundle With a Bedside Checklist to Reduce Mortality During the Initial COVID-19 Pandemic and Implications for Future Emergencies.

Objective: The study objective was to examine the effectiveness of a bedside checklist enforcing nursing-led interventions in hospitalized COVID-19 patients early in the pandemic.

Background: The absence of treatment guidelines for COVID-19 presented challenges to reducing mortality rates early in the pandemic. A bedside checklist and a bundle of nursing-led interventions named "Nursing Back to Basics (NB2B)" were assembled for patient care after a scoping review of evidence.

Anchor threads can double the insect flight energy absorbed by spider orb webs.

To successfully capture flying insect prey, a spider's orb web must withstand the energy of impact without the silk breaking. In this study, we examined the anchor threads: the silk lines that anchor the main capture area of the web to the surrounding environment. These anchor threads can account for a large portion of the web, yet are usually excluded from experiments and simulations.

Depletion of skeletal muscle satellite cells attenuates pathology in muscular dystrophy.

Skeletal muscle can repair and regenerate due to resident stem cells known as satellite cells. The muscular dystrophies are progressive muscle wasting diseases underscored by chronic muscle damage that is continually repaired by satellite cell-driven regeneration. Here we generate a genetic strategy to mediate satellite cell ablation in dystrophic mouse models to investigate how satellite cells impact disease trajectory.

Eicosatetraynoic Acid and Butyrate Regulate Human Intestinal Organoid Mitochondrial and Extracellular Matrix Pathways Implicated in Crohn's Disease Strictures.

Background: Perturbagen analysis of Crohn's disease (CD) ileal gene expression data identified small molecules including eicosatetraynoic acid (ETYA), which may exert an antifibrotic effect. We developed a patient-specific human intestinal organoid (HIO) model system to test small molecule regulation of mitochondrial and wound-healing functions implicated in stricturing behavior.

Methods: HIOs were made from CD induced pluripotent stem cells with and without a loss-of-function haplotype in the DUOX2 gene implicated in ileal homeostasis and characterized under basal conditions and following exposure to butyrate and ETYA using RNA sequencing, flow cytometry, and immunofluorescent and polarized light microscopy.

Emerging Technology: Preparing Tomorrow's MCH Workforce to Innovate for Equity.

Purpose: This commentary proposes a new direction to train the MCH workforce by leveraging today's rapidly changing innovation and technology to address persistent health inequities.

Description: We outline the creation of an MCH technology and innovation training pipeline developed by harnessing creative funding opportunities, diversifying training modalities, and expanding partnerships beyond traditional academic-practice partners, that be replicated and adapted by other academic programs.

Assessment: Technology and innovation will continue to be a growing intersection between health and equity, and we must create a robust pipeline of MCH leaders prepared to collaborate with entrepreneurial and innovation leaders.

Permanent deformation of triangle weaver silk enables ultrafast tangle-free release of spider webs.

Entanglements are common in both natural and artificial systems and can result in both beneficial and harmful effects. Most spider webs are static structures held under constant tension and do not tangle. However, many spiders actively load tension into their webs by coiling silk threads that are released to "fire" webs at prey.

Young people's romantic relationships and sexual activity before and during the COVID-19 pandemic.

Background: Social distancing measures to reduce the spread of COVID-19 may profoundly impact young people's relationships. This study compared adolescent and young adults' romantic relationships and sexual activity before and after social distancing policies were enacted.

Methods: In June 2020, 351 youth participating in an ongoing intervention study in Fresno County, California completed an online survey about their experiences related to COVID-19.

Slingshot spiders build tensed, underdamped webs for ultrafast launches and speedy halts.

We develop a mathematical model to capture the web dynamics of slingshot spiders (Araneae: Theridiosomatidae), which utilize a tension line to deform their orb webs into conical springs to hunt flying insects. Slingshot spiders are characterized by their ultrafast launch speeds and accelerations (exceeding 1300 [Formula: see text]), however a theoretical approach to characterize the underlying spatiotemporal web dynamics remains missing. To address this knowledge gap, we develop a 2D-coupled damped oscillator model of the web.

The Woodhull Study Revisited: Nurses' Representation in Health News Media 20 Years Later.

Purpose: To determine if nurses are represented in health news stories more frequently today than 20 years ago when Sigma Theta Tau International Nursing Honorary Society published The Woodhull Study on Nursing and the Media, which found that nurses were cited as sources in only 4% of the stories.

Design: Content analysis of health news stories for the month of September 2017 in the same publications used in the original Woodhull study.

Methods: Searches with Nexis and Webhose identified 2,243 articles related to health care published by the news outlets in September 2017.

Clinical nutrition in primary care: An evaluation of resident physicians' attitudes and self-perceived proficiency.

Background & Aims: There is little information regarding the impact of clinical nutrition training among medical residents. We aimed to evaluate the attitudes, self-perceived proficiency and knowledge of Swiss residents regarding clinical nutrition.

Methods: Cross-sectional study conducted between June and September 2014 in two medical education facilities located in Lausanne, Switzerland.

Outcome of Allogeneic Hematopoietic Stem Cell Transplantation for Patients with Chronic and Advanced Phase Myelofibrosis.

Myelofibrosis (MF) is a chronic progressive hematologic malignancy with a median overall survival (OS) of approximately 6 years. Allogeneic hematopoietic stem cell transplantation (HSCT) is the sole treatment approach that offers curative potential. The use of reduced-intensity conditioning regimens has expanded the application of HSCT to patients with MF up to age 70 years.

Patient perspectives on post-discharge surgical site infections: towards a patient-centered mobile health solution.

Background: Post-discharge surgical site infections (SSI) are a major source of morbidity, expense and anxiety for patients. However, patient perceptions about barriers experienced while seeking care for post-discharge SSI have not been assessed in depth. We explored patient experience of SSI and openness to a mobile health (mHealth) wound monitoring "app" as a novel solution to address this problem.

Plasmodium falciparum infection rates for some Anopheles spp. from Guinea-Bissau, West Africa.

Presence of Plasmodium falciparum circumsporozoite protein (CSP) was detected by enzyme linked immunosorbent assay (ELISA) in a sample of Anopheles gambiae s.s., A.

An analysis of two island groups as potential sites for trials of transgenic mosquitoes for malaria control.

Considerable technological advances have been made towards the generation of genetically modified mosquitoes for vector control. In contrast, less progress has been made towards field evaluations of transformed mosquitoes which are critical for evaluating the success of, and hazards associated with, genetic modification. Oceanic islands have been highlighted as potentially the best locations for such trials.