Publications by authors named "Sarah Fittro"
Article Synopsis
- Children with sickle cell disease (SCD) often experience abdominal pain, which may be linked to various gastrointestinal (GI) issues, but there's limited data on how frequently this occurs or how it’s evaluated.
- A study analyzed 1279 encounters of children with abdominal pain, finding that 23% were associated with such pain, particularly in older children with sickle cell anemia (SCA) and those with specific blood count parameters.
- Less than half of these patients received a GI-specific evaluation in the emergency department, suggesting that improving these evaluations could help diagnose or rule out GI problems and expand the understanding of abdominal pain in SCD patients.
Key Points: Electrical synapses are modified by various forms of activity, including paired activity in coupled neurons and tetanization of the input to coupled neurons. We show that plasticity of electrical synapses that results from paired spiking activity in coupled neurons depends on calcium influx and calcium-initiated signalling pathways. Plasticity that results from tetanization of input fibres does not depend on calcium influx or dynamics.
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