Publications by authors named "Sarah F Frisken"

Article Synopsis
  • Surgical resection remains the main approach for treating brain tumors, but traditional navigation methods struggle with brain movement during surgery.
  • A new system improves surgical guidance by using the positions of instruments to create an accurate map of tumor removal in real-time, evaluated through 80 surgeries.
  • While the system estimates residual tumors well under ideal conditions, it still provides valuable insights even when brain shift occurs, helping surgeons detect areas that may need further attention.
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We extend 3D SurfaceNets to generate surfaces of segmented 3D medical images composed of multiple materials represented as indexed labels. Our extension generates smooth, high-quality triangle meshes suitable for rendering and tetrahedralization, preserves topology and sharp boundaries between materials, guarantees a user-specified accuracy, and is fast enough that users can interactively explore the trade-off between accuracy and surface smoothness. We provide open-source code in the form of an extendable C++ library with a simple API, and a Qt and OpenGL-based application that allows users to import or randomly generate multi-label volumes to experiment with surface fairing parameters.

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Purpose: We present SlicerDMRI, an open-source software suite that enables research using diffusion magnetic resonance imaging (dMRI), the only modality that can map the white matter connections of the living human brain. SlicerDMRI enables analysis and visualization of dMRI data and is aimed at the needs of clinical research users. SlicerDMRI is built upon and deeply integrated with 3D Slicer, a National Institutes of Health-supported open-source platform for medical image informatics, image processing, and three-dimensional visualization.

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Brain shift during tumor resection compromises the spatial validity of registered preoperative imaging data that is critical to image-guided procedures. One current clinical solution to mitigate the effects is to reimage using intraoperative magnetic resonance (iMR) imaging. Although iMR has demonstrated benefits in accounting for preoperative-to-intraoperative tissue changes, its cost and encumbrance have limited its widespread adoption.

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