Publications by authors named "Sarah Elizabeth Heywood"
Article Synopsis
- Gastric emptying plays a crucial role in managing post-meal blood sugar levels, and the delay in gastric emptying is linked to improved glucose control with GLP-1 analogs.
- Researchers found that increased levels of interleukin (IL)-6 slow down gastric emptying, leading to lower blood sugar levels after meals.
- IL-6 also decreases insulin secretion in a way that depends on GLP-1, and these effects were confirmed after exercise; this finding could lead to new treatments for managing gastric emptying and insulin secretion in individuals with type 2 diabetes.
HDL and glucose metabolism: current evidence and therapeutic potential.
Front Pharmacol
November 2015
High-density lipoprotein (HDL) and its principal apolipoprotein A-I (ApoA-I) have now been convincingly shown to influence glucose metabolism through multiple mechanisms. The key clinically relevant observations are that both acute HDL elevation via short-term reconstituted HDL (rHDL) infusion and chronically raising HDL via a cholesteryl ester transfer protein (CETP) inhibitor reduce blood glucose in individuals with type 2 diabetes mellitus (T2DM). HDL may mediate effects on glucose metabolism through actions in multiple organs (e.
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