Several tick-borne pathogens from the Anaplasmataceae family, including Ehrlichia and Anaplasma, have been identified as causing diseases like human monocytic ehrlichiosis and granulocytic anaplasmosis, raising health concerns.
Despite the challenges posed by host immune systems, these rickettsials have adapted mechanisms to survive and thrive in both tick and vertebrate hosts, influencing their gene expression depending on the environment.
The review emphasizes the significance of understanding tick-Ehrlichia interactions and their implications for future research in this area.