Neurodevelopmental outcome at 6 months of age of full-term neonates with hyperbilirubinemia necessitating exchange transfusion.

Background: Bilirubin neurotoxicity involves a spectrum of varying severity that could result in adverse long-term sequelae.

Aims: To compare the neurodevelopmental outcome of full-term neonates who underwent exchange transfusion with those who did not.

Study Design: A retrospective cohort study.

The spectrum of bilirubin neurotoxicity in term and near-term babies with hyperbilirubinemia: Does outcome improve with time?

Background: While neonatal jaundice is generally a common benign condition; severe hyperbilirubinemia has a devastating potential for brain injury.

Aim: To detect the impact of severe neonatal hyperbilirubinemia on motor and mental development and its progress over time in the first year of life using the Bayley scales of infant development (BSID) II.

Study Design And Patients: 177 term/near-term infants admitted for neonatal hyperbilirubinemia to the NICU of Cairo University Children's Hospital were enrolled.

Factors affecting cerebrovascular reactivity to CO2 in premature infants.

Background Hypercarbia increases cerebral blood flow secondary to cerebral vasodilatation, while hypocarbia can lead to vasoconstriction with a subsequent decrease in cerebral blood flow. The aim of this study was to examine CO2 cerebral vasoreactivity in a cohort of premature infants and to identify factors which influence this reactivity. Methods We prospectively studied a cohort of hemodynamically stable premature infants [birth weight (BW) <1500 g and gestational age (GA) ≤34 weeks].