Publications by authors named "Sarah E Dedonder"
Background: Ehrlichia chaffeensis is an emerging tick-borne rickettsial pathogen responsible for human monocytic ehrlichiosis. Despite the induction of an active host immune response, the pathogen has evolved to persist in its vertebrate and tick hosts. Understanding how the organism progresses in tick and vertebrate host cells is critical in identifying effective strategies to block the pathogen transmission.
View Article and Find Full Text PDFMolecular characterization of Ehrlichia interactions with tick cells and macrophages.
Front Biosci (Landmark Ed)
January 2009
Article Synopsis
- Several tick-borne pathogens from the Anaplasmataceae family, including Ehrlichia and Anaplasma, have been identified as causing diseases like human monocytic ehrlichiosis and granulocytic anaplasmosis, raising health concerns.
- Despite the challenges posed by host immune systems, these rickettsials have adapted mechanisms to survive and thrive in both tick and vertebrate hosts, influencing their gene expression depending on the environment.
- The review emphasizes the significance of understanding tick-Ehrlichia interactions and their implications for future research in this area.