Publications by authors named "Sarah Chairani Zakirah"
Future of Health Services: The Role of Physicians in the Disruptive Era.
J Hum Reprod Sci
December 2020
This article aimed to address the role of physicians in future health in the disruptive era. Physicians in this disruptive era must increase their capability and knowledge to compensate for this development. Advances in technology increase the impact on health care and the significance of disruption.
View Article and Find Full Text PDFArticle Synopsis
- Poor ovarian reserve and high pregnancy failure rates are linked to low oocyte quality and quantity in women considered poor responders to IVF.
- This study involved 749 women to analyze the impact of factors like age, BMI, endometriosis, and previous ovarian surgeries on their ovarian reserve status.
- Findings indicated that age and AMH levels were significant predictors, with age being the strongest factor, while endometriosis and surgical history also played roles in different Poseidon classification groups.
Background: Ca signaling pathway is suggested to play an essential role in mediating oocyte maturation.
Aims: The aim of this study was to evaluate intracellular Ca of resistant immature oocytes that failed to resume meiosis following subsequent culture reach metaphase II after calcium ionophore A23187 activation.
Settings And Design: This analytical experimental study was conducted at Animal Science Laboratory of Indonesian Medical Education and Research Institute (IMERI), Human Reproductive Infertility and Family Planning of IMERI, and Electrophysiology Imaging of Terpadu Laboratory, Faculty of Medicine, University of Indonesia.
Background: Implantation failure has long been identified as a common problem underlying low success rate of IVF. Currently, endometrial receptivity has gained expert attention as it is demonstrated to contribute to successful embryo implantation. MicroRNAs (miRNAs) is known to affect endometrial receptivity through post-transcriptional gene expression regulation.
View Article and Find Full Text PDFBackground: Few studies have assessed the impact of serum human chorionic gonadotropin (hCG) levels before oocyte retrieval and luteinizing hormone receptor (LHR) mRNA expression.
Aims: The objective was to assess the correlations between serum hCG levels at 12-h posttrigger granulosa cell LHR mRNA expression during the fertilization (IVF) cycle with oocyte maturation rate and to determine the cutoff level of serum hCG at 12-h posttrigger.
Settings And Design: A cross-sectional was conducted for this study at the IVF center of Dr.