Publications by authors named "Sarah Carron"
We used functional magnetic resonance imaging (fMRI) to investigate spatial working memory (WM) in an N-BACK task (0, 1, and 2-BACK) in premanifest Huntington's disease (pre-HD, n = 35), early symptomatic Huntington's disease (symp-HD, n = 23), and control (n = 32) individuals. Overall, both WM conditions (1-BACK and 2-BACK) activated a large network of regions throughout the brain, common to all groups. However, voxel-wise and time-course analyses revealed significant functional group differences, despite no significant behavioral performance differences.
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- The study explores neurogenesis following diffuse traumatic brain injury (TBI) in rats, an area not previously examined despite its prevalence in human cases.
- Researchers induced traumatic axonal injury (TAI) using an impact-acceleration model and used a labeling technique to track cell proliferation in the brain.
- Findings show increased proliferation of certain cells in specific brain regions after TAI, but ultimately, there wasn't a significant increase in the production of new neurons, indicating a strong glial response rather than new neuron development.