Publications by authors named "Sarah Camboim Del Rio Naiz"
Toxicol Ind Health
November 2023
Article Synopsis
- Manganese is a common element that's important for biological functions, but long-term exposure can lead to Manganism, a disorder similar to Parkinson's disease caused by mitochondrial issues and oxidative stress.
- This study explored the neuroprotective effects of probucol, a compound known for its anti-inflammatory and antioxidant properties, on brain slices from rats exposed to manganese chloride.
- Results showed that probucol effectively prevented manganese toxicity, maintaining cell viability and protecting mitochondrial function in the brain regions tested, highlighting its potential as an antioxidant therapy.
