Insulin resistance is higher in prepubertal girls but switches to become higher in boys at age 16: A Cohort Study (EarlyBird 57).

Background: The risk of type 2 diabetes is increasing in teenage girls, and is associated with their greater insulin resistance (IR).

Hypothesis: We hypothesized that the adverse metabolic profile of girls (compared with boys) would persist from childhood through adolescence.

Patients And Methods: Community-based longitudinal cohort of 292 children (147 boys) studied annually from 9 to 16 years.