Seracam: characterisation of a new small field of view hybrid gamma camera for nuclear medicine.

Background: Portable gamma cameras are being developed for nuclear medicine procedures such as thyroid scintigraphy. This article introduces Seracam® - a new technology that combines small field of view gamma imaging with optical imaging - and reports its performance and suitability for small organ imaging.

Methods: The count rate capability, uniformity, spatial resolution, and sensitivity for Tc are reported for four integrated pinhole collimators of nominal sizes of 1 mm, 2 mm, 3 mm and 5 mm.

Efficient Retrieval of Images with Irregular Patterns Using Morphological Image Analysis: Applications to Industrial and Healthcare Datasets.

Image retrieval is the process of searching and retrieving images from a datastore based on their visual content and features. Recently, much attention has been directed towards the retrieval of irregular patterns within industrial or healthcare images by extracting features from the images, such as deep features, colour-based features, shape-based features, and local features. This has applications across a spectrum of industries, including fault inspection, disease diagnosis, and maintenance prediction.

Intraoperative Gamma Cameras: A Review of Development in the Last Decade and Future Outlook.

Portable gamma cameras suitable for intraoperative imaging are in active development and testing. These cameras utilise a range of collimation, detection, and readout architectures, each of which can have significant and interacting impacts on the performance of the system as a whole. In this review, we provide an analysis of intraoperative gamma camera development over the past decade.

Charge Sharing and Charge Loss in High-Flux Capable Pixelated CdZnTe Detectors.

Cadmium zinc telluride (CdZnTe) detectors are known to suffer from polarization effects under high photon flux due to poor hole transport in the crystal material. This has led to the development of a high-flux capable CdZnTe material (HF-CdZnTe). Detectors with the HF-CdZnTe material have shown promising results at mitigating the onset of the polarization phenomenon, likely linked to improved crystal quality and hole carrier transport.

Assessing a small field of view hybrid gamma camera for perioperative iodine-125 seed localisation.

Objective: To examine the imaging capability of a novel small field of view hybrid gamma camera (HGC) using I seeds prior to surgical use.

Methods: The imaging performance of the camera system was assessed quantitatively and qualitatively at different source depths, source to collimator distances (SCD), activity levels, acquisition times and source separations, utilising bespoke phantoms.

Results: The system sensitivity and spatial resolution of the HGC for I were 0.

A novel compact small field of view hybrid gamma camera: first clinical results.

Introduction: Hybrid imaging has proven to be a major innovation in nuclear medicine, allowing the fusion of functional information with anatomical detail. In the past, the use of hybrid imaging such as PET-CT, PET-MRI and SPECT-CT has been of great clinical benefit; however, these scanners are relatively large and bulky. We have developed and investigated the clinical application of a compact small field of view hybrid gamma camera (HGC) that is suitable for small-organ imaging at the patient bedside.

Design and implementation of a prototype head and neck phantom for the performance evaluation of gamma imaging systems.

Background: A prototype anthropomorphic head and neck phantom has been designed to simulate the adult head and neck anatomy including some internal organs and tissues of interest, such as thyroid gland and sentinel lymph nodes (SLNs). The design of the head and neck phantom includes an inner jig holding the simulated SLNs and thyroid gland. The thyroid gland structure was manufactured using three-dimensional (3D) printing taking into consideration the morphology and shape of a healthy adult thyroid gland.

A Multimodality Hybrid Gamma-Optical Camera for Intraoperative Imaging.

The development of low profile gamma-ray detectors has encouraged the production of small field of view (SFOV) hand-held imaging devices for use at the patient bedside and in operating theatres. Early development of these SFOV cameras was focussed on a single modality-gamma ray imaging. Recently, a hybrid system-gamma plus optical imaging-has been developed.

Quantitative investigation of a novel small field of view hybrid gamma camera (HGC) capability for sentinel lymph node detection.

Objective: The hybrid gamma camera (HGC) has been developed to enhance the localization of radiopharmaceutical uptake in targeted tissues during surgical procedures such as sentinel lymph node (SLN) biopsy. To assess the capability of the HGC, a lymph node contrast (LNC) phantom was constructed to simulate medical scenarios of varying radioactivity concentrations and SLN size.

Methods: The phantom was constructed using two clear acrylic glass plates.

Assessment of the performance of small field of view gamma cameras for sentinel node imaging.

Objective: To develop a method for the assessment of small field of view (SFOV) gamma cameras using a novel phantom designed to simulate the localization of sentinel nodes in the presence of a high-activity injection site.

Materials And Methods: The phantom consisted of a cube-shaped acrylic glass support frame. Sixteen acrylic glass plates and nine bars were stacked within the frame to allow a variable configuration of the simulated node depth and node-to-injection site separation.