External Human-Machine Interfaces for Automated Vehicles in Shared Spaces: A Review of the Human-Computer Interaction Literature.

Given the rise of automated vehicles from an engineering and technical perspective, there has been increased research interest concerning the Human and Computer Interactions (HCI) between vulnerable road users (VRUs, such as cyclists and pedestrians) and automated vehicles. As with all HCI challenges, clear communication and a common understanding-in this application of shared road usage-is critical in order to reduce conflicts and crashes between the VRUs and automated vehicles. In an effort to solve this communication challenge, various external human-machine interface (eHMI) solutions have been developed and tested across the world.

Inflammatory bowel disease and endothelin-1: a review.

Inflammatory bowel disease (IBD) appears to be an inappropriate response to an antigen that leads to chronic inflammation rather than repair. This review looks at the role of endothelin-1 (ET-1) as a proinflammatory agent in IBD. ET-1 antagonists in animal models reduce the incidence and severity of IBD.