Publications by authors named "Sarah Bourdon"

Giving birth prematurely is a traumatic event that has many consequences for the mother but also for her baby and their family. Studies have shown that about a quarter of these mothers will suffer from post-traumatic stress disorder (PTSD) as a result. This study aims to identify internal personality factors associated with the development of PTSD in mothers who gave birth before 33 weeks.

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Agricultural landscapes are increasingly characterized by intensification and habitat losses. Landscape composition and configuration are known to mediate insect abundance and richness. In the context of global insect decline, and despite 75% of crops being dependent on insects, there is still a gap of knowledge about the link between pollinators and aromatic crops.

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Background: The next generation of prosthetic limbs will restore sensory feedback to the nervous system by mimicking how skin mechanoreceptors, innervated by afferents, produce trains of action potentials in response to compressive stimuli. Prior work has addressed building sensors within skin substitutes for robotics, modeling skin mechanics and neural dynamics of mechanotransduction, and predicting response timing of action potentials for vibration. The effort here is unique because it accounts for skin elasticity by measuring force within simulated skin, utilizes few free model parameters for parsimony, and separates parameter fitting and model validation.

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In response to ramp-and-hold indentation, the slowly-adapting type I (SAI) afferent exhibits an exponential decrease in its firing frequency during the hold phase. Such adaptation may be tied to skin relaxation but is neither well understood nor has it been quantitatively modeled. The specific hypothesis of this work is that skin relaxation is a primary contributor to observed changes in firing rate.

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Activation of the receptor tyrosine kinase Axl recruits signaling molecules that regulate cell growth and survival. To evaluate Axl's role in brain during cuprizone toxicity, mice were fed cuprizone and evaluated at 3-, 4-, and 6-week cuprizone treatment and 3- and 5-week post-cuprizone withdrawal. At 4-week cuprizone treatment, the corpora callosa of wildtype (WT) mice had robust Oil Red O+ staining indicative of ongoing phagocytosis.

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