Publications by authors named "Sarah Besora"
Introduction: Neuroprotective drugs such as citicoline could improve cognitive performance and quality of life. We studied the effect of citicoline treatment and its association with Vascular Risk Factors (VRF) and APOE on cognition in patients with Subjective Cognitive Complaints (SCC) and Mild Cognitive Impairment (MCI).
Methods: This is an observational and prospective study with citicoline during 12 months follow-up.
The objective of this observational study was to evaluate the efficacy and safety of duloxetine in a cohort of 100 cancer survivors with chemotherapy-induced peripheral neurotoxicity (CIPN). CIPN was graded employing the TNSc and the NCI-CTCv4. The Patient Global Impression of Change (PGIC) scale measured the efficacy of duloxetine (1: no benefit; to 7: excellent response).
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- Acenocoumarol is a blood thinner that shows different dosage needs among individuals due to genetic differences, specifically variants in CYP2C9 and VKORC1 genes.
- Researchers conducted a study on 78 Spanish stroke patients using a genome-wide association study to identify genetic variants linked to acenocoumarol dosage and complications like stroke recurrence and intracranial hemorrhage.
- They found 14 genetic variants related to dosage, with specific ones linked to stroke recurrence (6 variants) and intracranial hemorrhage (4 variants), emphasizing the importance of pharmacogenetic studies for improving anticoagulant therapy safety and effectiveness.
Bruns-Garland syndrome (diabetic amyotrophy) is associated with a rapid improvement in metabolic control.
Endocrinol Diabetes Nutr (Engl Ed)
March 2020
Background: Oxaliplatin (OXA) is a cornerstone in the treatment of colorectal cancer (CRC). Retreatment with OXA is frequently considered as salvage treatment. OXA-induced neuropathy (OIN) is the most frequent and feared long-term side effect.
View Article and Find Full Text PDFBackground: Primary central nervous system lymphomas may present as diffuse, nonenhancing infiltrative lesions. This rare variant is termed lymphomatosis cerebri (LC). We did a systematic review and analysis of the literature, adding our own cases, to better characterize LC in order to improve early diagnosis and treatment.
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