Publications by authors named "Sarah Benevenuto"

Article Synopsis
  • This study explores how exposure to cannabis smoke during pregnancy affects brain development in offspring, using pregnant mice as subjects.* -
  • The research found that male foetuses exposed to cannabis smoke had initially decreased brain volumes, but showed increased volumes in certain brain areas by postnatal day 60, indicating complex developmental changes.* -
  • Key findings include an increase in brain-derived neurotrophic factor (BDNF) expression and altered cell viability in neurons treated with cannabis smoke extract, suggesting potential negative impacts on neurodevelopment.*
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Article Synopsis
  • Air pollution is a big health problem around the world, especially in places like São Paulo, Brazil, where many people and cars create a lot of harmful gases and particles.
  • Exposure to tiny particles in the air can hurt our DNA, and a protein called XPC helps repair this DNA damage.
  • Research on mice showed that when XPC is not working properly, pollution causes more inflammation and DNA damage, proving that XPC is important for protecting against the dangers of air pollution.
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Air pollution is a public health concern that has been associated with adverse effects on the development and functions of the central nervous system (CNS). However, studies on the effects of exposure to pollutants on the CNS across the entire developmental period still remain scarce. In this study, we investigated the impacts of prenatal and/or postnatal exposure to fine particulate matter (PM) from São Paulo city, on the brain structure and behavior of juvenile male mice.

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The prevalence of marijuana use among pregnant women is high. However, the effects on gestation and fetal development are not well known. Epidemiological and experimental studies present conflicting results because of the route of administration, dose, time of exposure, species used, and how Cannabis toxicity is tested (prepared extracts, specific components, or by pyrolysis).

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