Impact of preoperative antibiotics and other variables on integrated microbiome-host transcriptomic data generated from colorectal cancer resections.

Background: Integrative multi-omic approaches have been increasingly applied to discovery and functional studies of complex human diseases. Short-term preoperative antibiotics have been adopted to reduce site infections in colorectal cancer (CRC) resections. We hypothesize that the antibiotics will impact analysis of multi-omic datasets generated from resection samples to investigate biological CRC risk factors.

Core Measures for Congestive Heart Failure in a Tertiary Care Setting in Pakistan.

Purpose:  Heart failure presents a huge burden for individual patients and the healthcare system as a whole. This study aims to assess the adherence to these core measures as identified by the Joint Commission on Accreditation of Healthcare Organizations (JCAHO)/ American Heart Association (AHA) by physicians of Pakistan.

Materials And Methodology:  We conducted a cross-sectional study in Shifa International Hospital, Islamabad, Pakistan from the period of April 2013 to April 2016.

Constraining Dark Matter Interactions with Pseudoscalar and Scalar Mediators Using Collider Searches for Multijets plus Missing Transverse Energy.

The monojet search, looking for events involving missing transverse energy (E_{T}) plus one or two jets, is the most prominent collider dark matter search. We show that multijet searches, which look for E_{T} plus two or more jets, are significantly more sensitive than the monojet search for pseudoscalar- and scalar-mediated interactions. We demonstrate this in the context of a simplified model with a pseudoscalar interaction that explains the excess in GeV energy gamma rays observed by the Fermi Large Area Telescope.