Publications by authors named "Sarah A Kromrey"
Article Synopsis
- The study evaluates physiological and behavioral traits in female cynomolgus monkeys to understand social hierarchy and its health impacts.
- Baseline measurements of hormones like estradiol, progesterone, cortisol, and testosterone were taken, revealing that lower body weight and higher estradiol levels predicted subordinate status.
- Findings indicated that subordinate monkeys faced increased stress and cognitive challenges, highlighting the relevance of this model for studying stress-related human diseases.
Preclinical research has demonstrated that cognitive function may be influenced by estradiol (E2) and progesterone (P4) concentrations, although few cognition studies involve normally cycling females. The present study examined cognitive performance in normally cycling female cynomolgus macaques (n = 14), a species with similarities to humans in brain organization and a nearly identical menstrual cycle to women. Initial assessments compared cognitive measures to circulating concentrations of E2 and P4 (n = 12).
View Article and Find Full Text PDFEffects of prior cocaine self-administration on cognitive performance in female cynomolgus monkeys.
Psychopharmacology (Berl)
June 2015
Cocaine use has been associated with cognitive impairments that may contribute to poor treatment outcomes. However, the degree to which these deficits extend into periods of abstinence has not been completely elucidated. This study tested whether prior experience self-administering cocaine affected acquisition of two cognitive tasks in 16 adult female cynomolgus monkeys.
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