SNMMI Clinical Trial Network Research Series for Technologists: Application of Good Clinical Practice to Clinical Research in Medical Imaging.

This article is part of a series developed by the Clinical Trials Network of the Society of Nuclear Medicine and Molecular Imaging to offer training and information for molecular imaging technologists and researchers about various aspects of clinical research. This article covers the topic of good clinical practice and how that relates to those portions of the that govern clinical research in the United States, such as title 21, part 312, and the Common Rule. The purpose of this article is to inform technologists and researchers about standard roles, documents, guidance, and processes that are elemental to the conduct of clinical trials and to offer additional resources for learning about these processes.

Ancillary Finding on Myocardial Perfusion Imaging Due to Urinary Bladder Displacement.

When imaging patients are referred for single-photon emission computed tomography (SPECT) myocardial perfusion imaging (MPI) with technetium 99m (Tc) agents, the attention is focused on the tracer activity in the myocardium. Apart from myocardial activity, the normal biodistribution of Tc Sestamibi and Tc Tetrofosmin is seen in the thyroid, liver, gastrointestinal tract, kidneys, and urinary bladder. These structures may be visualized when a large field of view (FOV) gamma camera is used for SPECT imaging.

SNMMI Clinical Trials Network Research Series for Technologists: Clinical Research Primer-Regulatory Process, Part I: How and When Radiopharmaceuticals Can Be Used.

For CE credit, you can access the test for this article, as well as additional CE tests, online at https://www.snmmilearningcenter.org Complete the test online no later than March 2025.

Novel Method to Detect and Characterize F-FDG Infiltration at the Injection Site: A Single-Institution Experience.

A novel quality control and quality assurance device provides time-activity curves that can identify and characterize PET/CT radiotracer infiltration at the injection site during the uptake phase. The purpose of this study was to compare rates of infiltration detected by the device with rates detected by physicians. We also assessed the value of using the device to improve injection results in our center.