Publications by authors named "Sarah A Barnes"
Structural insights into RNA cleavage by a novel family of bacterial RNases.
Nucleic Acids Res
September 2024
Article Synopsis
- The study focuses on Escherichia coli's YicC protein, a newly identified ribonuclease crucial for RNA processing in living organisms.
- Researchers have characterized the structure of YicC in two forms: an unbound state (apo) and one bound to RNA, revealing unique structural features like a clamshell shape that are different from known ribonucleases.
- Findings highlight the importance of a specific domain (DUF1732) in RNA binding and catalytic activity, providing new insights into the functions of the YicC RNase family.