Publications by authors named "Sara Sorrenti"
Twin pregnancies account for 3% of all pregnancies and they are burdened by higher morbidity and mortality compared to singletons. The role of ultrasound in the screening, diagnosis and management of possible complications of twin pregnancies has been widely investigated in the current literature. However, despite the progress that have been made in the last decades regarding treatment and evidence-based management of complications, twin pregnancies remain at higher risk of adverse outcomes, requiring therefore dedicated surveillance.
View Article and Find Full Text PDFTwin pregnancies are at increased risk of morbidity and mortality compared to singletons. Among all twins, monochorionic pregnancies are at higher risk of specific and non-specific complications compared to dichorionic pregnancies. Therefore, it is of great importance to properly counsel future parents with monochorionic pregnancies regarding the risks of adverse outcomes and the modalities of monitoring and intervention of the potential complications.
View Article and Find Full Text PDFArticle Synopsis
- The systematic review aimed to determine if early hospital discharge after cesarean delivery affects maternal readmission rates by analyzing data from multiple electronic databases.
- Only randomized controlled trials (RCTs) comparing early (within 24-28 hours) and late (≥48 hours) discharge after cesarean delivery were included in the review.
- Findings showed no significant difference in maternal readmission rates between early and late discharge groups, but early discharge was linked to better psychological wellbeing and cost-effectiveness.
The aim of this systematic review is to report the normal cortical development of different fetal cerebral fissures on ultrasound, describe associated anomalies in fetuses with cortical malformations, and evaluate the quality of published charts of cortical fissures. The inclusion criteria were studies reporting development, anomalies, and reference charts of fetal cortical structures on ultrasound. The outcomes observed were the timing of the appearance of different cortical fissures according to different gestational age windows, associated central nervous system (CNS) and extra-CNS anomalies detected at ultrasound in fetuses with cortical malformation, and rate of fetuses with isolated anomaly.
View Article and Find Full Text PDFObjective: Counseling of pregnancies complicated by pre- and periviable premature rupture of membranes to reach shared decision-making is challenging, and the current limited evidence hampers the robustness of the information provided. This study aimed to elucidate the rate of obstetrical and neonatal outcomes after expectant management for premature rupture of membranes occurring before or at the limit of viability.
Data Sources: Medline, Embase, CINAHL, and Web of Science databases were searched electronically up to September 2023.
Counseling in fetal medicine: Congenital cytomegalovirus infection.
Eur J Obstet Gynecol Reprod Biol
April 2024
Although the clinical work-up of CMV in pregnancy has gradually become more accurate, counseling for CMV is still challenging. Despite the potential feasibility of universal prenatal serological screening, its introduction in prenatal diagnosis continues to raise concerns related to its real cost-effectiveness. Contextually, anticipating the confirmation of fetal infection earlier in pregnancy is one of the most pressing issues to reduce the parental psychological burden.
View Article and Find Full Text PDFObjective: To evaluate maternal and perinatal outcomes of removal versus retention of cervical cerclage after premature preterm rupture of membranes (pPROM).
Study Design: Medline, Embase and Cochrane databases were searched electronically on February 2023 utilizing combinations of the relevant medical subject heading (MeSH) terms, keywords, and word variants that were considered suitable for the topic. Either prospective or retrospective trials were considered suitable for the inclusion.
Article Synopsis
- A recent study explores the effects of CFTR modulators, specifically Elexacaftor/Tezacaftor/Ivacaftor, in pregnant women with cystic fibrosis, an area with limited existing data about potential side effects.
- The case reported shows a woman experienced significant improvement in her respiratory health during pregnancy after resuming CFTR modulation in the second and third trimesters, after initially stopping due to safety concerns.
- The pregnancy proceeded without major complications, resulting in a healthy baby, suggesting that using these CFTR modulators in pregnancy may not pose significant risks and could enhance patient management.
Objective: To assess evidence on the efficacy of adjuvant human papillomavirus (HPV) vaccination in patients treated for HPV-related disease across different susceptible organ sites.
Methods: A systematic review was conducted to identify studies addressing the efficacy of adjuvant HPV vaccination on reducing the risk of recurrence of HPV-related preinvasive diseases. Results were reported as mean differences or pooled odds ratios (OR) with 95% confidence intervals (95% CI).