Objectives: Neuropsychiatric symptoms and anosognosia are known to influence the perceived quality of life of patients (QoL-p) with Alzheimer's disease (AD). This study analysed their impact on patient and caregiver ratings of QoL-p and how these ratings changed in relation to the severity of dementia.
Methods: A baseline sample of 221 patients and caregivers was followed up over 24 months.
Introduction: Anosognosia and depression can influence perceptions of the patient's quality of life (QoL-p) in Alzheimer's disease (AD).
Aim: To explore changes in perceived QoL-p in AD and the influence that depression and anosognosia can have on both patient and caregiver ratings.
Patients And Methods: Observational, analytical and longitudinal study over 12 months of a consecutive sample of 221 outpatients.