Publications by authors named "Sara Pickett"
Article Synopsis
- - The study addresses the challenge of inter-batch variability in untargeted metabolomics for screening inborn errors of metabolism (IEMs) by creating a matrix-matched reference material (RM) using the iterative batch averaging (IBAT) method.
- - The RM showed significantly lower variability in amino acid concentrations over time compared to conventional specimen pools, making it effective in normalizing data from different batches.
- - When tested in screening phenylketonuria (PKU) patients, the RM successfully distinguished between PKU patients and controls, demonstrating its potential for improving clinical diagnostic capabilities.
Background: Bereavement support is a key component of palliative care, with different types of support recommended according to need. Previous reviews have typically focused on specialised interventions and have not considered more generic forms of support, drawing on different research methodologies.
Aim: To review the quantitative and qualitative evidence on the effectiveness and impact of interventions and services providing support for adults bereaved through advanced illness.
Article Synopsis
- - The study focused on creating a Core Outcome Set (COS) for evaluating bereavement support in palliative care by gathering perspectives from stakeholders to standardize what outcomes should be measured in research.
- - Researchers combined insights from a literature review and discussions at an expert workshop, followed by an international DELPHI survey with 240 participants, to identify and prioritize key outcomes essential for bereavement support assessment.
- - Two core outcomes were selected: 'Ability to cope with grief' and 'Quality of life and mental wellbeing,' with 21 specific dimensions highlighted to assess these outcomes, covering various aspects like communication, understanding grief, and maintaining social connections.
Introduction: Radiotherapy treatment for prostate cancer can cause bowel problems, which may lead to severe difficulties for cancer survivors including limiting travel, work or socialising. These symptoms can appear at any time following radiotherapy. This study focuses on the early identification and protocol-based management of effects known to cause long-term, or even permanent, changes to the well-being of prostate cancer survivors.
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