Publications by authors named "Sara Nsibirwa"

The global spread of antimicrobial resistance (AMR) poses an increasing challenge for clinicians in Uganda, where microbiological diagnostics are not routinely available or accessible. The aim of this study was to determine pathogen prevalence and antibiotic resistance patterns in patients with wound infections following trauma at a national referral hospital in Kampala, Uganda. In addition, the suitability of currently used empirical treatment options in this setting was evaluated.

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Article Synopsis
  • Health workers in Uganda are not following the Ministry of Health guidelines for screening and managing HIV-associated cryptococcal meningitis (CM), which is a concerning public health issue.
  • An observational study assessed adherence at 15 different health facilities between January and June 2021, using a scoring system; the average adherence score was only 64.7%, indicating poor compliance.
  • Key findings revealed that many health facilities lacked essential resources, such as potassium chloride, and failed to conduct necessary baseline tests for patients, highlighting a significant gap in care for individuals at risk of CM.
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Background: HIV infection is associated with more rapid progression of some comorbidities. This study assessed the impact of HIV-infection on the presentation and outcome of HCC.

Methods: HCC patients attending the Mulago National Referral Hospital in Uganda were enrolled into a natural history study of HCC between March 2015 and February 2019.

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Nosocomial wound infections are a dreaded complication in patients with burns. However, access to the necessary microbiological diagnostics is impaired in low-resource settings. This prospective observational cohort study aimed to describe the bacterial pathogens, resistance profiles and clinical outcomes of patients with wound infections admitted to the largest specialized unit for burns and plastic surgery in Uganda.

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Background: There is some evidence that patients with liver diseases commonly use complementary and alternative therapies to address general and liver-disease specific health concerns. The purpose of this study was to assess and describe prevalence, patterns and related factors of herbal medicine use among adults diagnosed with viral and non-viral hepatitis in Kampala, Uganda.

Methods: A cross-sectional study was conducted on 310 adult patients attending the gastrointestinal clinic in Mulago hospital referral hospital in Kampala.

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