Utility of Tc-Sestamibi Heart/Liver Uptake Ratio in Screening Nonalcoholic Fatty Liver Disease During Myocardial Perfusion Imaging.

Nonalcoholic fatty liver disease (NAFLD) is the most common chronic hepatic disease worldwide, with functional impairment of the mitochondria occurring from early stages. Technetium-99m methoxy-isobutyl-isonitrile (Tc-MIBI) is a lipophilic agent trapped in the mitochondria. This study aims to evaluate the utility of Tc-MIBI heart/liver uptake ratio in screening for NAFLD during myocardial perfusion imaging (MPI).