Publications by authors named "Sara Morrone"

Impaired lipid metabolism is a pivotal driver of cardiovascular disease (CVD). In this regard, the accumulation of ceramides within the circulation as well as in metabolically active tissues and atherosclerotic plaques is a direct consequence of derailed lipid metabolism. Ceramides may be at the nexus between impaired lipid metabolism and CVD.

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Article Synopsis
  • HDL-cholesterol distribution in subfractions plays a significant role in cardiovascular health risk, particularly for pre- and postmenopausal women.
  • The study found that overweight women and those with high CVD risk had lower cholesterol in large HDL subfractions, while factors like insulin resistance and visceral fat negatively affected this distribution.
  • Diet quality influences HDL cholesterol levels, with higher energy intake linked to lower large HDL cholesterol and higher lipid intake associated with increased small HDL cholesterol.
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