Role of the dorsolateral prefrontal cortex in processing temporal anomalies retained in working memory.

Introduction: Time is a crucial abstract construct, allowing us to perceive the duration of events. Working memory (WM) plays an important role in manipulating and storing the different features of environmental stimuli, including temporal features. Different brain structures, including the dorsolateral prefrontal cortex, are involved in time processing.

The time squares sequences: a new task for assessing visuospatial working memory.

Introduction: Several studies have shown that the working memory is sensitive to temporal variations. We used a new visuospatial working memory task, the "Time Squares Sequences," to investigate whether implicit variations in stimuli presentation time affect task performance.

Methods: A total of 50 healthy participants saw two sequences (S1 and S2) of seven white squares presented in a matrix of gray squares and assessed whether S2 matched S1.