Publications by authors named "Sara McFarlane"
J R Soc Interface
September 2008
Article Synopsis
- Understanding how cells respond to their environment shapes could lead to advancements in creating artificial environments for biomimetic surfaces, particularly benefiting regenerative medicine.
- The study compares gene profiles of mesenchymal stem cells on different nanoscale topographies to those treated with dexamethasone, revealing that physical changes in the matrix can trigger similar cellular responses as chemical stimulation.
- The findings indicate that using matrix topography can promote bone formation efficiently while preserving endothelial cell development, highlighting the importance of matrix shape in tissue engineering.
