Publications by authors named "Sara Mambrilla Herrero"

Background: Intraductal papillary neoplasm of the bile ducts (IPNB) is a rare disease in Western countries. The aim of this study was to compare tumor characteristics, management strategies, and outcomes between Western and Eastern patients who underwent surgical resection for IPNB.

Methods: A multi-institutional retrospective series of patients with IPNB undergoing surgery between January 2010 and December 2020 was gathered under the auspices of the European-African Hepato-Pancreato-Biliary Association (E-AHPBA), and at Nagoya University Hospital, Japan.

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Article Synopsis
  • The study investigates surgical methods and outcomes for Intraductal Papillary Neoplasm of the Bile Duct (IPNB) across 28 European centers, highlighting its rarity in Western countries.
  • Out of 85 patients analyzed (median age 66), open surgery was more common, and a significant portion achieved the "textbook outcome" (TO) indicating successful surgery without major complications.
  • Key findings suggest that factors like patient comorbidities, tumor characteristics, and the type of surgical resection impact overall survival, with achieving TO being a critical factor for better prognosis.
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Testicular germ cell tumors, though rare (1%), represent the most common neoplasm among young men. Gastrointestinal involvement from these malignancies usually presents as bowel obstruction and digestive bleeding, but their frequency is low (5%). The patterns of this involvement are: infiltration from affected retroperitoneal lymph nodes or, less frequently, by peritoneal seeding and direct hematogenous spread.

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