Publications by authors named "Sara Lovati"
Article Synopsis
- The study aimed to assess the outcomes of high-risk HPV-positive and negative women with high-grade cervical dysplasia through a retrospective analysis of medical records from 2010 to 2014.
- A total of 2,966 women were included, with 85% being HR-HPV-positive; results indicated that HR-HPV-positive patients had a significantly higher risk of recurrence after conization compared to HR-HPV-negative patients.
- The findings suggest that while HR-HPV-negative high-grade dysplasia accounts for 15% of cases, these patients generally have better outcomes, highlighting the need for further research to validate these results.
Previous studies on breast and ovarian carcinoma (BC and OC) revealed constitutional and promoter hypermethylation as epigenetic alterations leading to tumor predisposition. Nevertheless, the impact of epimutations at these genes is still debated. One hundred and eight women affected by BC, OC, or both and considered at very high risk of carrying germline mutations were studied.
View Article and Find Full Text PDFIn August 2016, a magnitude 6.0 earthquake struck Central Italy, starting a devastating seismic sequence, aggravated by other two events of magnitude 5.9 and 6.
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