Effect of thalidomide on growth and metastasis of canine osteosarcoma cells after xenotransplantation in athymic mice.

Objective: To determine whether thalidomide inhibits the growth of primary and pulmonary metastatic canine osteosarcoma in mice after xenotransplantation.

Animals: Athymic nude mice.

Procedure: Canine osteosarcoma cells were injected SC in 50 mice.