Potentially reversible acute cerebellar toxicity associated with Minnelide.

Purpose: Minnelide is an experimental antineoplastic agent that is currently the subject of a phase 1 clinical trial for the treatment of pancreatic and gastrointestinal malignancies. In this study, we documented two cases of reversible acute cerebellar toxicity (REACT) associated with Minnelide and compared its radiological manifestations with other cerebellotoxic agents.

Methods: Both patients had histories of progressive metastatic cancer and participated in a phase 1 clinical trial with Minnelide.

All that bleeds is not black: susceptibility weighted imaging of intracranial hemorrhage and the effect of T1 signal.

Purpose: To determine if intracranial hemorrhages (ICH) are always hypointense on Susceptibility weighted imaging (SWI) and to determine the effect of T1-signal intensity on the appearance of ICH in SWI series.

Methods: SWI and T1-signal intensities of ICH were retrospectively studied in a series of patients. SWI signal intensities were statistically correlated with T1-signal intensities.

Susceptibility-weighted imaging in stroke-like migraine attacks after radiation therapy syndrome.

Introduction: Stroke-like migraine attacks after radiation therapy (SMART) syndrome has a characteristic clinical presentation and postcontrast T1WI MRI appearance. Susceptibility-weighted imaging (SWI) may help distinguish SMART from other disorders that may have a similar postcontrast MRI appearance.

Methods: The MRI examinations of four patients with SMART syndrome are described herein, each of which included SWI, FLAIR, DWI, and postcontrast T1WI on the presenting and follow-up MRI examinations.

Determinants of patient satisfaction with ultrasound-assisted liposuction.

Background: Liposuction is one of the most common aesthetic procedures and a number of options are available to practitioners in terms of surgical technique. One of those options is ultrasound-assisted liposuction (UAL), which has garnered considerable attention in the literature and from patients themselves. Because the role of ultrasound in body sculpting is continuing to increase over time, the authors believe that a comprehensive assessment of patient satisfaction after the procedure is essential.

Hospital admission due to nephrological conditions during Hajj: causes, healthcare use, and short-term outcomes.

In this retrospective study, records of Iranian Hajj pilgrims who were hospitalized in 2 Iranian hospitals in Mecca and Medina, Saudi Arabia, from 2005 to 2007, were reviewed. Of 600 patients who were hospitalized, 12 (2.0%) were admitted due to nephrological causes, which included kidney calculi (n = 7; 58.

Pattern of glomerulonephritis in Iran: a preliminary study and brief review.

Background: Glomerulonephritis is a relatively rare disease with numerous subtypes and limited numbers of patients with each. Comprehensive epidemiological surveys are therefore difficult to undertake and there are few data on the spectrum of renal disease, especially in Iran. The aim was to determine the pattern of glomerulonephritis in Iran.