Publications by authors named "Sara Karimzadeh"

This article discusses the importance of a multilevel and intertwined understanding of ethical consumption given its conjunction with other social practices. Although the literature on ethical consumption is vast, the role of sociotechnical regimes including technological and cultural elements, infrastructure, market and regulation has been mainly overlooked in this literature. This may be so because ethical consumption practices that refer to other-oriented consumption practices are mainly considered in the view of the motivations and preferences of individual consumers.

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Background: Different types of non-hepatorenal tyrosinemia are among the rare forms of tyrosinemia. Tyrosinemia type II and III are autosomal recessive disorders caused by pathogenic variants in the tyrosine aminotransferase (TAT), and 4-hydroxyphenyl-pyruvate dioxygenas (HPPD) genes, respectively. There are still unclarified aspects in their clinical presentations, mutational spectrum, and genotype-phenotype correlation.

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Introduction: Liver transplantation (LT) is the choice of therapeutic option for end-stage hepatic GSD patients; however, reports about the long-term outcome of LT in these patients have remained controversial.

Methods: We performed a systematic review and meta-analysis of observational studies published until Dec 31, 2021, that investigated the long-term outcome of LT in hepatic GSD patients. A literature search in the MEDLINE/PubMed, EMBASE,Cochrane Library, Scopus and Web of Science Core Collection databases was performed.

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Introduction: Islet transplantation has been introduced as a promising approach for the treatment of diabetes mellitus type 1. Despite many efforts to achieve a perfect treatment, further investigation is still needed to eliminate limitations and challenging issues. The objective of the present systematic review is to evaluate the efficacy of islet transplantation in diabetes mellitus type 1.

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Background: The impact of anti-HLA donor-specific alloantibodies (DSA) which develop after long-term liver transplantation (LT) remains controversial and unclear. The aim of this study was to investigate the role of DSAs on the outcome in LT.

Methods: We did a systematic review and meta-analysis of observational studies published until Dec 31, 2019, that reported DSA outcome data (≥1 year of follow-up) after liver transplant.

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Article Synopsis
  • Glycogen storage diseases (GSDs) affecting the liver are challenging to diagnose due to gene diversity and reliance on invasive methods like tissue sampling.
  • A systematic review analyzed studies from multiple databases, focusing on patients with liver-involved GSDs and evaluating targeted gene sequencing (TGS) and exome sequencing (ES).
  • The results showed that ES had a 93% diagnostic yield while TGS had about 79.7%, suggesting TGS as a first-line tool and ES for more complex cases, making these methods efficient and cost-effective for diagnosis and treatment.
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