Role of lenalidomide in the treatment of multiple myeloma and myelodysplastic syndrome.

Objective: To evaluate lenalidomide in the treatment of multiple myeloma and myelodysplastic syndrome (MDS).

Data Sources: Clinical literature was accessed through MEDLINE (1966-August 2005), Science Citation Index (1980-August 2005), and Proceedings of the American Society of Hematology (2000-2004).

Data Synthesis: New analogs of thalidomide have been synthesized that are more potent and less toxic.