Publications by authors named "Sara J Mason"
Article Synopsis
- Long noncoding RNAs (lncRNAs), particularly BORG, play significant roles in breast cancers but have been under-researched in large tumor cohorts and across different subtypes.
- BORG expression is found to be elevated in breast tumors compared to normal tissues, with considerable variability in expression levels across tumor subtypes and even among tumors of the same subtype.
- The study identifies BORG as a key factor linked to aggressive cancer pathways, especially in triple-negative breast cancers (TNBC), suggesting it could drive the development of this aggressive tumor phenotype.
Objective: In this study we examined the temporal stability of the Immediate Post-Concussion Assessment and Cognitive Test (ImPACT) within NCAA Division I athletes across various timepoints using an exhaustive series of statistical models.
Methods: Within a cohort design, 48 athletes completed repeated baseline ImPACT assessments at various timepoints. Intraclass correlation coefficients (ICC) were calculated using a two-way mixed effects model with absolute agreement.
The latest Neoproterozoic extinction of the Ediacara biota has been variously attributed to catastrophic removal by perturbations to global geochemical cycles, 'biotic replacement' by Cambrian-type ecosystem engineers, and a taphonomic artefact. We perform the first critical test of the 'biotic replacement' hypothesis using combined palaeoecological and geochemical data collected from the youngest Ediacaran strata in southern Namibia. We find that, even after accounting for a variety of potential sampling and taphonomic biases, the Ediacaran assemblage preserved at Farm Swartpunt has significantly lower genus richness than older assemblages.
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