Publications by authors named "Sara J Lawrence-Mills"
Background: Reindeer are becoming popular animals within petting farms. Few case reports describe the sedation of domesticated reindeer, but none describe the use of ocular local anesthetic blocks in this species.
Case Description: A 9-year-old, female, Svalbard reindeer ( ) presenting for removal of a squamous cell carcinoma involving the third eyelid.
The endothelial glycocalyx (eGlx) is a critically important structure lining the luminal surface of endothelial cells. There is increasing evidence, in human patients and animal models, for its crucial role in the maintenance of health. Moreover, its damage is associated with the pathogenesis of multiple disease states.
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- The endothelial glycocalyx (eGlx) is a vital layer on endothelial cells that helps maintain vascular health, and its damage is linked to various diseases.
- This study used established techniques to visualize the eGlx in the microvasculature of reproductive tissues in five healthy dogs during elective neutering, focusing on uterine and testicular arteries.
- The results showed that eGlx was successfully visualized in the arteries of two dogs, revealing specific depths, but highlighted the need for further research to improve methods for measuring eGlx health in clinical settings.
The endothelial glycocalyx (eGlx) lines the luminal surface of endothelial cells, maintaining vascular health. Glycocalyx damage is pathophysiologically important in many diseases across species however few studies have investigated its breakdown in naturally occurring disease in dogs. The aims of the study were to investigate eGlx damage in dogs with myxomatous mitral valve disease (MMVD) diagnosed on echocardiography, and dogs in a hypercoagulable state diagnosed using thromboelastography (TEG), by measuring serum hyaluronan concentrations.
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