Treatment patterns, health care resource utilization, and costs associated with use of atypical antipsychotics as first vs subsequent adjunctive treatment in major depressive disorder.

Major depressive disorder (MDD) is a highly prevalent mental health condition associated with substantial economic burden. Inadequate response to first-line antidepressant monotherapy is common, with most patients requiring 1 or more changes in their treatment regimen. Adjunctive treatment with atypical antipsychotics (AAs) is a guideline-recommended treatment option in patients with inadequate response.

Place of care and costs associated with acute episodes and remission in schizophrenia.

Schizophrenia imposes significant economic burden on patients, families, caregivers, and society. To our knowledge, place of care and associated costs of acute schizophrenia episodes have not been well characterized. To describe the care settings and costs associated with likely acute episodes and untreated remission periods among patients with schizophrenia.

Place of care and costs associated with acute episodes and remission in bipolar I disorder.

Aims: To our knowledge, literature describing the place of care and associated costs during acute bipolar I disorder (BP-I) episodes is limited. We conducted a claims-based retrospective study to address this gap.

Materials And Methods: Adults with BP-I were identified via IBM MarketScan Commercial and Medicare Supplemental databases.

Treatment Patterns During Major Depressive Episodes Among Patients with Major Depressive Disorder: A Retrospective Database Analysis.

Background: Major depressive disorder, a highly prevalent mental health condition, can be challenging to treat.

Objective: We aimed to characterize treatment patterns within and across multiple major depressive episodes in patients receiving treatment for major depressive disorder.

Methods: Adults with newly diagnosed major depressive disorder and one or more major depressive episodes were identified using the IBM MarketScan Commercial database.

Psoriasis treatment patterns: a retrospective claims study.

The objective was to characterize psoriasis treatment patterns, including estimating persistence and describing subsequent events (i.e. switching and restarting) for all systemic therapies.