Effect of Topical 2% Eucalyptus Extract on 5-FU-Induced Oral Mucositis in Male Golden Hamsters.

Oral mucositis is a common inflammatory complication among patients with cancer. This study evaluated the histopathological, stereological, and antioxidant markers of 2% eucalyptus extract in induced oral mucositis in male golden hamsters. In this animal study, oral mucositis was induced in 30 male golden hamsters by 5-FU (60 mg/kg) on days 0, 5, and 10 of the study.

Protective effect of bilberry extract as a pretreatment on induced oral mucositis in hamsters.

Objective: This study evaluated the effect of standardized bilberry extract containing anthocyanosides on chemotherapy-induced oral mucositis in hamsters.

Study Design: Twenty-four hamsters were randomly chosen and assigned to groups. Groups A and B were pretreated with deionized water, whereas group C was pretreated with bilberry extract daily for 7 days.