Front Bioeng Biotechnol
October 2023
The use of biocompatible scaffolds combined with the implantation of neural stem cells, is increasingly being investigated to promote the regeneration of damaged neural tissue, for instance, after a Spinal Cord Injury (SCI). In particular, aligned Polylactic Acid (PLA) microfibrils' scaffolds are capable of supporting cells, promoting their survival and guiding their differentiation in neural lineage to repair the lesion. Despite its biocompatible nature, PLA is an electrically insulating material and thus it could be detrimental for increasingly common scaffolds' electric functionalization, aimed at accelerating the cellular processes.
View Article and Find Full Text PDFBackground: Pre-hospital emergency medical systems do not appear to work totally coordinated with Accident and Emergency (A&E). Often, patient admission to A&E is marked by scarce attention to the handover between the respective healthcare professionals. This phenomenon is potentially dangerous because it exposes patients to the risk of errors in a context where the patients' critical or progressing conditions must not be worsened by avoidable errors of communication between professionals.
View Article and Find Full Text PDFNumerical evaluation of the electromagnetic (EM) quantities induced inside the brain during transcranial magnetic stimulation (TMS) applications is a fundamental step to obtain the optimization of the treatment in terms of coil position and current intensity. In this sense, the human head model considered and the electromagnetic properties used to characterize the tissues have an influence on the EM solution. Thus, the aim of this study is to evaluate how different skin conductivities and different computational head models, i.
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