Publications by authors named "Sara Fattori"

Rationale: Limbic encephalitis is one of the most common paraneoplastic neurological disorders (PND). The role of brain Fluorine-18-fluorodeoxyglucose position emission tomography/computed tomography (CT) in paraneoplastic limbic encephalitis (PLE) and of the whole body 18F-FDG PET/CT in this setting, remains still not well defined.

Patient Concerns: We report a case of a patient with chronic inflammatory rheumatism, psoriasis and Hashimoto thyroiditis and subsequent appearance of static and dynamic ataxia and episodic memory deficit who was diagnosed as PLE combined with small cell lung cancer (SCLC).

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Article Synopsis
  • A multicenter study compared the effectiveness of two doses of 131-iodine (1850 MBq vs. 3700 MBq) for thyroid ablation in differentiated thyroid cancer patients who were prepped with recombinant human TSH (rhTSH).
  • Both doses achieved a high successful ablation rate of around 88.9%, with similar undetectable serum thyroglobulin levels in the two groups.
  • The study concluded that a lower dose of 1850 MBq is just as effective as the higher dose for thyroid ablation in patients, including those with node metastases.
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  • The study aimed to assess how fused images from CT and FDG-PET scans can help in defining gross tumor volume (GTV) and clinical target volume (CTV) for radiation therapy planning.
  • Involving 28 patients with lung cancer and non-Hodgkin's lymphoma, the research found that PET scans changed the GTV or CTV in 44% of cases, impacting treatment strategies.
  • The results highlight that FDG-PET offers enhanced visualization of tumor spread, confirming that combining CT and PET imaging can significantly improve radiation therapy planning and overall patient management.
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