An association between bilateral keratoconus in a patient with spondyloocular syndrome and xylosyltransferase II gene mutation.

Spondyloocular syndrome (SOS) is a rare autosomal-recessive disorder. Since 2015, SOS has been linked to mutations in xylosyltransferase II () locus. Phenotypic features could affect multiple systems, such as sight, hearing, or bones.