Publications by authors named "Sara Faour"
Article Synopsis
- - Tinea capitis is a contagious fungal infection affecting children, with significant public health implications due to its prevalence, risk factors, and potential long-term effects if untreated; regional variations exist in causative agents, primarily Trichophyton in North America and Microsporum globally.
- - Diagnosis primarily involves clinical evaluation, microscopic examination, and fungal culture, while treatment options include systemic antifungals, particularly terbinafine for Trichophyton infections; accurate diagnosis and patient education are critical for successful outcomes.
- - Preventative measures focus on early detection and healthy habits, emphasizing the need for collaboration between healthcare providers and public health agencies to improve treatment effectiveness and community awareness to reduce the infection's spread.
Background: Pattern hair loss, the most common form of hair loss, affects millions in the United States. Americans are increasingly seeking health information from social media. It would appear that healthcare professionals contribute relatively minimally to pattern hair loss content, thereby posing serious concerns for credibility and quality of information available to the general public.
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- Burn injuries lead to hypermetabolic reprogramming, increasing the risk of illness and death, yet the mechanisms behind this response are not well understood.
- The study identifies that changes in protein S-acylation in key metabolic organs like adipose tissue and the liver contribute to harmful outcomes post-burn injury, with alterations in various signaling pathways.
- Targeting S-acylation with a DHHC inhibitor shows promise in reducing detrimental effects like ER stress and increased lipolysis, suggesting a new therapeutic approach to enhance recovery after burns.
Scar development remains a common occurrence and a major healthcare challenge affecting the lives of millions of patients annually. Severe injuries to the skin, such as burns can lead to pathological wound healing patterns, often characterized by dermal fibrosis or excessive scarring, and chronic inflammation. The two most common forms of fibrotic diseases following burn trauma are hypertrophic scars (HSCs) and keloids, which severely impact the patient's quality of life.
View Article and Find Full Text PDFT cells use their T-cell receptors (TCRs) to discriminate between lower-affinity self and higher-affinity foreign peptide major-histocompatibility-complexes (pMHCs) based on the TCR/pMHC off-rate. It is now appreciated that T cells generate mechanical forces during this process but how force impacts the TCR/pMHC off-rate remains debated. Here, we measured the effect of mechanical force on the off-rate of multiple TCR/pMHC interactions.
View Article and Find Full Text PDFPeriodontal disease can lead to bacteremia with release of cytokines, affecting implantation in women trying to conceive through in vitro fertilization (IVF). A potential association between maternal periodontal disease and poor IVF outcomes has been described. The aim of the study is to assess whether pre-existing periodontal disease has any effect on IVF parameters.
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