Enhanced human periodontal ligament stem cell viability and osteogenic differentiation on two implant materials: An experimental study.

Surface roughness of dental implants impacts the survival of adult periodontal stem cells and rate of differentiation. This research was conducted to test how human periodontal ligament stem cells behaved on yttria stabilized tetragonal zirconia polycrystals and polyetheretherketone (PEEK) discs with different surface topographies. Discs roughening was prepared by sandblasting.

Effect of local application of platelet-rich fibrin scaffold loaded with simvastatin on peri-implant bone changes.

Aim: The purpose of this study was to compare the effects of autologous platelet-rich fibrin (PRF) alone and PRF loaded with SIM on peri-implant bone changes and implant stability in patients undergoing implant rehabilitation.

Settings And Design: This was a nonrandomized controlled split-mouth study.

Materials And Methods: The study included 8 males between the ages of 45 and 60 years.