Front Endocrinol (Lausanne)
October 2023
Objective: To evaluate the value of the thyrotropin-releasing hormone (TRH) test in the diagnosis of central hypothyroidism (CH) in patients with pituitary disease.
Methods: Systematic evaluation of 359 TRH tests in patients with pituitary disease including measurements of thyroxine (T4), TBG-corrected T4 (T4), baseline TSH (TSH) and relative or absolute TSH increase (TSH, TSH).
Results: Patients diagnosed with CH (n=39) show comparable TSH (p-value 0.