Publications by authors named "Sara E Mahoney"

Background: The purpose of this study was to compare the effects of supplementing habitual run training with periodized lower body strength training versus high intensity circuit strength training on running performance and related variables in experienced runners.

Methods: Nineteen (N.=19) participants performed 8 weeks of 2 d·wk periodized lower body strength training (PLB), N.

View Article and Find Full Text PDF

Purpose: This study longitudinally compared changes in running performance (5-km time trial) and fitness (maximal oxygen uptake [VO2max] and body composition [BC]) between polarized training and CrossFit Endurance (CFE) in recreational runners.

Methods: Participants (N = 21) completed 12 wk of CFE or polarized endurance training (POL). Both groups trained 5 d·wk-1.

View Article and Find Full Text PDF

Purpose: Considerable research has shown adverse neurobiological effects of chronic alcohol use, including long-term and potentially permanent changes in the structure and function of the brain; however, much less is known about the neurobiological consequences of chronic smoking, as it has largely been ignored until recently. In this article, we present a conceptual model proposing the effects of smoking on neurocognition and the role that physical activity may play in this relationship as well as its role in smoking cessation.

Methods: Pertinent published peer-reviewed articles deposited in PubMed delineating the pathways in the proposed model were reviewed.

View Article and Find Full Text PDF

The marathon is considered one of the most demanding endurance events, imposing an enormous amount of physiological stress on bodily structures, the metabolic machinery, and organ systems. Scientific evidence has conclusively shown that marathoners are in need of special nutritional strategies to maintain performance and health. Indeed, among competitive athletes, marathoners are at greater risk to develop anemia, bone mineral density loss, immunosuppression, and other clinical syndromes that may affect performance.

View Article and Find Full Text PDF

Objective: (1) Determine the relationship between dietary flavonoid-rich fruit and vegetable consumption on diabetes-related biomarkers (e.g., HgbA1c) and diabetic retinopathy.

View Article and Find Full Text PDF

Emerging work demonstrates that serum bilirubin is a novel biomarker implicated in cardiovascular and metabolic diseases. However, we have a limited understanding of the influence of flavonoid-rich fruit and vegetable consumption on bilirubin levels, which was the purpose of this study. Data from the 2003 to 2006 National Health and Nutrition Examination survey were used (n = 1783; 18-85 years of age), with analyses performed in 2014.

View Article and Find Full Text PDF

Purpose: While fatigue is the most commonly reported symptom of chemotherapy, there are currently no effective treatments for chemotherapy-induced fatigue (CIF). We used a mouse model to examine the benefits of quercetin on CIF as measured by voluntary wheel running activity and sought to determine whether quercetin may be associated with a decrease in inflammation and/or anemia.

Methods: Mice were assigned to 1 of 4 groups: placebo-vehicle (Plac-PBS), placebo-5-fluorouracil (Plac-5FU), quercetin-vehicle (Quer-PBS), or quercetin-5-fluorouracil (Quer-5FU).

View Article and Find Full Text PDF