Development and Validation of a Photonumeric Scale for Evaluation of Infraorbital Hollows.

Background: A validated scale is needed for objective and reproducible comparisons of infraorbital hollows (i.e., tear troughs) before and after treatment in practice and clinical studies.

Development and Validation of a Photonumeric Scale for Evaluation of Static Horizontal Forehead Lines.

Background: A validated scale is needed for objective and reproducible comparisons of static forehead lines before and after treatment in practice and clinical studies.

Objective: To describe the development and validation of the 5-point photonumeric Allergan Forehead Lines Scale.

Methods: The Allergan Forehead Lines Scale was developed to include an assessment guide, verbal descriptors, morphed images, and real subject images for each scale grade.

Development and Validation of a Photonumeric Scale for Evaluation of Transverse Neck Lines.

Background: A validated scale is needed for objective and reproducible comparisons of horizontal neck lines before and after treatment in practice and clinical studies.

Objective: To describe the development and validation of the 5-point photonumeric Allergan Transverse Neck Lines Scale.

Methods: The Allergan Transverse Neck Lines Scale was developed to include an assessment guide, verbal descriptors, morphed images, and real subject images for each scale grade.

Development and Validation of a Photonumeric Scale for Evaluation of Facial Fine Lines.

Background: A validated scale is needed for objective and reproducible comparisons of facial fine lines before and after treatment in practice and clinical studies.

Objective: To describe the development and validation of the 5-point photonumeric Allergan Fine Lines Scale.

Methods: The Allergan Fine Lines Scale was developed to include an assessment guide, verbal descriptors, morphed images, and real subject images for each scale grade.

Development and Validation of a Photonumeric Scale for Evaluation of Facial Skin Texture.

Background: A validated scale is needed for objective and reproducible comparisons of facial skin roughness before and after aesthetic treatment in practice and in clinical studies.

Objective: To describe the development and validation of the 5-point photonumeric Allergan Skin Roughness Scale.

Methods: The scale was developed to include an assessment guide, verbal descriptors, morphed images, and real subject images for each grade.

Development and Validation of a Photonumeric Scale for Assessment of Chin Retrusion.

Background: A validated scale is needed for objective and reproducible comparisons of chin appearance before and after chin augmentation in practice and clinical studies.

Objective: To describe the development and validation of the 5-point photonumeric Allergan Chin Retrusion Scale.

Methods: The Allergan Chin Retrusion Scale was developed to include an assessment guide, verbal descriptors, morphed images, and real subject images for each scale grade.

Development and Validation of a Photonumeric Scale for Evaluation of Volume Deficit of the Temple.

Background: A validated scale is needed for objective and reproducible comparisons of temple appearance before and after aesthetic treatment in practice and clinical studies.

Objective: To describe the development and validation of the 5-point photonumeric Allergan Temple Hollowing Scale.

Methods: The scale was developed to include an assessment guide, verbal descriptors, morphed images, and real subject images for each grade.

Development and Validation of a Photonumeric Scale for Evaluation of Volume Deficit of the Hand.

Background: A validated scale is needed for objective and reproducible comparisons of hand appearance before and after treatment in practice and clinical studies.

Objective: To describe the development and validation of the 5-point photonumeric Allergan Hand Volume Deficit Scale.

Methods: The scale was developed to include an assessment guide, verbal descriptors, morphed images, and real-subject images for each grade.

Porokeratotic eccrine duct and hair follicle nevus (PEHFN) associated with keratitis-ichthyosis-deafness (KID) syndrome.

Porokeratotic eccrine ostial and dermal duct nevus is a rare hamartomatous malformation, histologically characterized by cornoid lamellae overlying dilated eccrine ostia. The nevus most commonly presents in the form of multiple filiform keratotic spines in a linear arrangement, usually on the distal extremities. Porokeratotic eccrine and hair follicle nevus is thought to be a variant of porokeratotic eccrine ostial and dermal duct nevus that additionally involves hair follicle infundibula.

Study of the efficacy and tolerability of 0.04% tretinoin microsphere gel for preadolescent acne.

Objectives: The goals were to assess the degree of improvement of facial acne after treatment with the 0.04% tretinoin microsphere gel (TMG) among patients 8 to 12 years of age and to assess tolerability and safety.

Methods: An open-label study was conducted with 40 patients 8 to 12 years of age (mean age: 10.

Acquired disorders of elastic tissue: Part II. decreased elastic tissue.

Elastic fibers in the extracellular matrix are integral components of dermal connective tissue. The resilience and elasticity required for normal structure and function of the skin are attributable to the network of elastic tissue. Advances in our understanding of elastic tissue physiology provide a foundation for studying the pathogenesis of elastic tissue disorders.

Acquired disorders of elastic tissue: part I. Increased elastic tissue and solar elastotic syndromes.

Elastic fibers in the extracellular matrix are an integral component of dermal connective tissue. The resilience and elasticity required for normal structure and function of the skin may be attributed to the network of elastic tissue. Advances in our understanding of elastic tissue physiology provide a foundation for studying the pathogenesis of elastic tissue disorders.

Changing paradigms in dermatology: information technology.

Medicine and specifically, dermatology, is undergoing enormous changes in the way in which it is practiced. Much of this is a result of a fundamental change in the manner in which information is exchanged through information technology. With the advent of more advanced telecommunications, imaging capabilities and information transfer, the very ways in which we examine patients, develop diagnoses and plan treatments as dermatologists have changed dramatically.

Mid-dermal elastolysis preceded by acute neutrophilic dermatosis.

Background: Mid-dermal elastolysis is a rare idiopathic elastic tissue disorder that is characterized by localized patches of finely wrinkled skin and a "band-like" loss of elastic tissue in the mid-reticular dermis. Lesions may be preceded by erythema and/or urticaria, and histological examination of inflamed lesional skin may demonstrate lymphohistiocytic dermal infiltration.

Case Report: We report a case of mid-dermal elastolysis in a 31-year-old woman who developed multiple erythematous and urticarial plaques on the arms and trunk.