Publications by authors named "Sara Baggio"

Objectives: The authors sought to evaluate the incidence, predictors, and outcomes of new permanent pacemaker implantation (PPI) after transcatheter aortic valve replacement (TAVR) with contemporary self-expanding valves (SEV).

Background: Need for PPI is frequent post-TAVR, but conflicting data exist on new-generation SEV and on the prognostic impact of PPI.

Methods: This study included 3,211 patients enrolled in the multicenter NEOPRO (A Multicenter Comparison of Acurate NEO Versus Evolut PRO Transcatheter Heart Valves) and NEOPRO-2 (A Multicenter Comparison of ACURATE NEO2 Versus Evolut PRO/PRO+ Transcatheter Heart Valves 2) registries (January 2012 to December 2021) who underwent transfemoral TAVR with SEV.

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Background: In recent years, transcatheter aortic valve replacement (TAVR) techniques and technology have continuously improved. Data regarding the impact of these advancements on outcomes in large real-world settings are still limited. The aim of this study was to investigate temporal trends and assess contemporary outcomes after TAVR with Evolut PRO/PRO+ supra-annular self-expanding valves.

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Background: The ACURATE neo2 (NEO2) and Evolut PRO/PRO+ (PRO) bioprostheses are new-generation self-expanding valves developed for transcatheter aortic valve replacement (TAVR).

Aims: We sought to compare the performance of the ACURATE neo2 and Evolut PRO/PRO+ devices.

Methods: The NEOPRO-2 registry retrospectively included patients who underwent TAVR for severe aortic stenosis with either the NEO2 or PRO devices between August 2017 and December 2021 at 20 centres.

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Article Synopsis
  • A high-volume center reported on using balloon-expandable (BE) stents to manage vascular complications following transcatheter aortic valve replacement (TAVR), noting that such complications remain common despite advancements in the procedure.
  • The study involved 78 patients who underwent BE stent implantation, achieving a technical success rate of 96.2%, with only one in-hospital death and no significant long-term issues such as leg ischemia or stent occlusion.
  • The findings suggest that BE stents effectively manage vascular issues post-TAVR, but further research is necessary to fully understand their long-term benefits and potential applications.
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Background: Transcatheter aortic valve replacement (TAVR) with the ACURATE neo device has been associated with a non-negligible incidence of paravalvular aortic regurgitation (AR). The new-generation ACURATE neo2 has been designed to mitigate this limitation.

Aims: The aim of the study was to compare TAVR with the ACURATE neo and neo2 devices.

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Article Synopsis
  • * In a cohort of 305 hospitalized patients, 62.3% exhibited myocardial injury, evidenced by abnormal electrocardiograms and echocardiograms indicating left ventricular and right ventricular dysfunction.
  • * The findings showed that in-hospital mortality rates increased significantly with the presence of myocardial injury and echocardiographic abnormalities, linking these conditions to a greater risk of death during hospitalization.
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